COVID toes is a phenomenon which began to be documented in Spain and Italy at the start of winter while in the initial wave of the novel coronavirus outbreak in 2020. The reviews were seeing a high amount of chilblains of the feet in people who have COVID-19. The news media latched on to these stories and lots of interest was paid to them. Plenty of fascination continues to be generated from the general public and health care professionals in the entire phenomenon of COVID toes.
There are many of pathological functions associated with COVID-19, including complications with the blood flow, the cytokine reactions and inflamation related processes that may modify the circulation in the feet that predispose the foot or toes to having chilblains. Chilblains really are a poor response of the microcirculation to changes in temperature. In the event the tiny arteries don't respond adequately, waste material build up in the skin resulting in an inflamation related response that is the chilblain. It is easy to observe just how COVID-19 may raise the probability of getting a chilblain. Many early on histological analyses from biopsies in the chilblains in those that have COVID-19 did report that there were elements of the infection contained in the tissues. On the other hand, various other studies have reported that there wasn't any, therefore it has begun to become fairly confusing in regards to what the link between the two entities are.
The problem is that with the passage of time and additional analysis there's an increasing amount of research that there's virtually no connection between COVID-19 and chilblains and the high frequency is simply a coincidence. There is one report from the Nordic countries that there has been virtually no increase in the amount of chilblains in those countries. Some other current investigations by means of biopsies along with post-mortem autopsy have found no coronavirus substances in the chilblains. There is speculation how the assumed increase in the occurrence in some countries would be a problem with the lifestyle alterations as a result of the lockdown through the pandemic and that they aren't actually part of the pathophysiological response of the infection. These kinds of lifestyle changes during the lockdown include things like being a lot more inactive, perhaps the less wearing of shoes, becoming more exposed to air-conditioning along with the constant warmness inside. These kinds of changes in lifestyle throughout lockdown may have been greater in countries like Spain and Italy and the alterations might not have been so much in the Nordic nations. In Nordic countries they might just be better with handling the issues about temperature changes that are regarded as a risk factor in chilblains. This could certainly simply be the reason for the different prevalence in the above regions.